This second edition volume expands on the previous edition with discussions on the latest techniques used to study synaptic transmissions. The chapters in this book are organized into six parts. Part One looks at the basic concepts, such as extracellular and intracellular recordings, and spatiotemporal effects of synaptic currents. Part Two describes the recording of synaptic currents, such as measuring kinetics of synaptic current and measuring reversal potentials. Part Three discusses basic experimentations of synaptic transmission and covers run-up and run-down, and amplitude. Parts Four and Five cover experimentations with computational components and molecular and visual components, such as measurement of a single synapse and electrophysiological and visual tags. Part Six explores in vivo recordings and talks about general considerations for in vivo exploration of synaptic plasticity. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.
Authoritative and thorough, Electrophysiological Analysis of Synaptic Transmission, Second Edition is a valuable resource that introduces graduate students and postdoctoral fellows to important topics in this field and also expands these topics to practical electrophysiological approaches.
Contents: فهرست فصول
Part I Basic Concepts1. Extracellular and Intracellular RecordingsNicholas Graziane and Yan Dong2. Electrical TheoryNicholas Graziane and Yan Dong3. AmplifiersNicholas Graziane and Yan Dong4. Salt EnvironmentNicholas Graziane and Yan Dong5. Patch Pipettes (Micropipettes)Nicholas Graziane and Yan Dong6. Spatiotemporal Effects of Synaptic CurrentNicholas Graziane and Yan Dong7. Perforated PatchNicholas Graziane and Yan DongPart II Recording of Synaptic Current8. Isolation of Synaptic CurrentNicholas Graziane and Yan Dong9. Fast and Slow Synaptic CurrentsNicholas Graziane and Yan Dong10. Measuring Kinetics of Synaptic CurrentNicholas Graziane and Yan Dong11. Measuring Presynaptic Release ProbabilityNicholas Graziane and Yan Dong12. Long-Term MeasurementsNicholas Graziane and Yan Dong13. Measuring Reversal PotentialsNicholas Graziane and Yan DongPart III Basic Experimentations of Synaptic Transmission14. AmplitudeNicholas Graziane and Yan Dong15. Pre- vs. Post-Synaptic EffectNicholas Graziane and Yan Dong16. Run-Up and Run-DownNicholas Graziane and Yan Dong17. Kinetics of Synaptic CurrentNicholas Graziane and Yan DongPart IV Experimentations with Computational Components18. Measurement of a Single SynapseNicholas Graziane and Yan Dong19. Measurement of Silent SynapsesNicholas Graziane and Yan Dong20. Dendritic PatchNicholas Graziane and Yan DongPart V Experimentations with Molecular and Visual Components21. Electrophysiological and Visual TagsNicholas Graziane and Yan DongPart VI In Vivo Recordings22. Extracellular RecordingsNicholas Graziane and Yan Dong23. General Considerations for In Vivo Exploration of Synaptic PlasticityXiyu Zhu and Anthony Grace24. Technical Considerations for In Vivo ElectrophysiologyXiyu Zhu and Anthony GraceSubject Index List…